Organooxygen compounds
Medchemexpress LLC Cp-640186 hydrochloride | 591778-70-0 | MFCD28167776 | 99.7% | 522.08 g/mol | C30H36ClN3O3 | 10 MG
CP-640186 hydrochloride is the hydrochloride salt of a research-grade acetyl-CoA carboxylase (ACC) inhibitor used in metabolic studies. It is orally active and cell-permeable, with reported low-nanomolar potency against ACC isoforms, and can stimulate muscle fatty acid oxidation. Intended for laboratory research use only.
- Inhibits acetyl-CoA carboxylase with reported IC50s of 53 nM (ACC1) and 61 nM (ACC2).
- Orally active and cell-permeable research compound.
- High purity suitable for biochemical assays and cellular studies.
- Solid, light yellow to pink appearance.
- Molecular weight 522.08 g/mol; formula C30H36ClN3O3.
- Available in multiple small vial sizes for dose-ranging experiments.
- For research use only; not for human or clinical applications.
Alkali Scientific Ninhydrin Reagent, 100 G
Ninhydrin Reagent, 100g is a chemical reagent primarily used for the detection of amino acids, peptides, and proteins. When applied, ninhydrin reacts with free amines, turning a purple color, which is commonly used for amino acid quantification in chromatography and electrophoresis. This reagent is widely utilized in laboratory settings for detecting and analyzing amino acids in biological samples, such as urine, blood, and tissue extracts. The 100g pack size is suitable for high-throughput laboratories and research facilities conducting multiple experiments or large-scale studies in proteomics and amino acid analysis. It plays an essential role in protein research and metabolic studies.
Medchemexpress LLC SB-612111 hydrochloride | 99.6% | 454.86 | 50 MG
SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). It exhibits selectivity for μ-, κ- and δ-receptors. It effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model.
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Powder: -20°C for 3 years, 4°C for 2 years. In solvent: -80°C for 6 months, -20°C for 1 month
- Solubility (In Vitro): DMSO: 15.62 mg/mL (34.34 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | 99.4% | 374.82 g/mol | C17H19ClN6O2 | 25 MG
Zoniporide hydrochloride hydrate is the hydrochloride hydrate salt of zoniporide, a potent and selective inhibitor of the sodium-hydrogen exchanger isoform 1 (NHE-1) used for research applications. It is provided as a high-purity solid suitable for in vitro and ex vivo studies of NHE-1 function and related cardiovascular and platelet biology.
- Potent and selective NHE-1 inhibition (human IC50 ~14 nM).
- Inhibits ex vivo NHE-1-dependent platelet swelling (IC50 ~59 nM).
- High purity (>99% by HPLC).
- Available as the hydrochloride hydrate salt for improved handling and stability.
- Molecular weight 374.82 g/mol; molecular formula C17H19ClN6O2.
- Supplied in small research quantities, e.g., 25 MG.
Medchemexpress LLC Antalarmin (hydrochloride) | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 25 MG
Antalarmin hydrochloride is a research-grade, non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist supplied as a solid for preclinical pharmacology and biochemical studies. Intended for laboratory research use only.
- High purity (≈99.9%).
- Molecular weight 415.01 g/mol.
- Molecular formula C24H35ClN4.
- Appearance: solid, white to light yellow.
- Storage: sealed at -20°C; in solution: -80°C for 6 months, -20°C for 1 month.
- Supplied with data sheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC GYKI 53655 hydrochloride | 143692-48-2 | MFCD01941362 | 98.4% | 388.85 g/mol | C19H21ClN4O3 | 50 MG
GYKI 53655 hydrochloride is the hydrochloride salt of GYKI 53655, a selective antagonist of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors used as a research tool in neuropharmacology. The compound is supplied as a light yellow solid with high purity and documented solubility properties.
- Selective antagonist of AMPA receptors for neuropharmacology research.
- High purity suitable for in vitro pharmacology.
- Soluble in DMSO and partially soluble in water with warming or sonication.
- Supplied as a solid with recommended storage at 4°C, protected from moisture.
- Molecular weight 388.85 g/mol and formula C19H21ClN4O3.
Medchemexpress LLC GGTI-2154 (hydrochloride) | 478908-50-8 | 98.1% | 456.97 | 25 MG
GGTI-2154 hydrochloride is a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM. It demonstrates over 200-fold selectivity for GGTase I compared to FTase (IC50=5600 nM). This product is suitable for cancer research. It is for research use only and not sold to patients.
- Potent and selective inhibitor of geranylgeranyltransferase I (GGTase I) with an IC50 of 21 nM.
- Shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM).
- Can be used for cancer research.
- Induces breast tumor regression in MMTV-ν-Ha-Ras transgenic mice (100 mg/kg/day; s.c. for 14 days).
- Inhibits A-549 tumor growth in nude mice by 60% (50 mg/kg/day; i.p. for 50 days).
Medchemexpress LLC Etifoxine (hydrochloride) | 56776-32-0 | 99.8% | 337.24 | 100 MG
Etifoxine hydrochloride is a non-benzodiazepine GABAergic compound that acts as a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. It exhibits anxiolytic and anticonvulsant properties in rodents. This product is intended for research and analytical applications.
- Positive allosteric modulator of GABAA receptors.
- Exhibits anxiolytic properties.
- Exhibits anticonvulsant properties.
- Intended for research and analytical applications.
Medchemexpress LLC Ladostigil hydrochloride | 209394-18-3 | >98.0% | 308.80 g·mol⁻1 | C16H21ClN2O2 | 25 MG
Ladostigil hydrochloride is the hydrochloride salt of ladostigil (TV-3326), a multifunctional, orally active research compound that combines cholinesterase inhibition with brain-selective monoamine oxidase inhibition. Provided as a white to off-white powder for research use only, it is used in preclinical studies of neuroprotection, cognitive impairment, and depression-related models.
- Dual activity: cholinesterase and monoamine oxidase inhibition.
- Hydrochloride salt form for increased solubility and stability.
- Purity >98.0%.
- Molecular weight 308.80 g·mol⁻1.
- White to off-white powder suitable for formulation and dosing studies.
- Certificate of analysis typically available on request.
Medchemexpress LLC mAChR-IN-1 hydrochloride | 119391-73-0 | MFCD01725710 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 10MG
mAChR-IN-1 hydrochloride is a research-grade muscarinic acetylcholine receptor antagonist provided as the hydrochloride salt. It exhibits high potency (IC50 = 17 nM) and is characterized by a defined molecular formula and high reported purity, making it suitable for in vitro pharmacology and biochemical assays.
- Potent mAChR antagonist (IC50 = 17 nM).
- Hydrochloride salt form for consistent handling.
- High reported purity (99.6%).
- Molecular weight 524.82 g/mol; formula C23H26ClIN2O2.
- Intended for in vitro research applications.
Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | MFCD01698392 | 99.0% | C22H31ClN2 | 100 MG
Aprindine hydrochloride is an Ib-class anti-arrhythmic agent primarily used in the study of atrial fibrillation and ventricular arrhythmias. It functions by stabilizing cardiac electrical activity through multiple mechanisms.
- Blocks sodium channels to reduce excitability and conduction velocity of cardiac muscle cells.
- Inhibits delayed potassium currents, prolonging the atrial effective refractory period.
- Inhibits atrial fibrillation.
- Regulates intracellular calcium ion concentration by inhibiting the Na+/Ca2+ exchange current.
Medchemexpress LLC VU0453379 hydrochloride | 98.0% | 471.03 | 25 MG
VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM.
- Highly selective
- CNS penetrant
- Positive allosteric modulator (PAM) of GLP-1R
Medchemexpress LLC W-7 isomer hydrochloride | 69762-85-2 | 99.7% | 377.33 g·mol⁻1 | C16H22Cl2N2O2S | 1 MG
W-7 isomer hydrochloride is the positional isomer of W-7 hydrochloride, a selective calmodulin antagonist. Provided for research use, the compound is supplied as a solid in multiple sizes and as a DMSO solution, and is intended for studies probing calcium-dependent signaling where calmodulin inhibition is required.
- High purity (99.65%).
- Molecular weight 377.33 g·mol⁻1.
- Available as solid and 10 mM DMSO solution.
- Offered in multiple pack sizes from milligram quantities to larger amounts.
- Documents available: data sheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC SB 271046 hydrochloride | 209481-24-3 | 99.9% | 488.45 | C20H23Cl2N3O3S2 | 5 MG
SB 271046 hydrochloride is a research-grade 5-HT6 (serotonin 6) receptor antagonist supplied as a solid powder in a 5 mg vial. The compound (CAS 209481-24-3) has formula C20H23Cl2N3O3S2 and a molecular weight of 488.45. It is intended for laboratory research only and is accompanied by supplier analytical data and safety documentation.
- High purity (99.9%) suitable for research applications.
- Supplied as a solid powder in a 5 mg vial.
- Includes supplier analytical data sheet and SDS.
- Suitable for in vitro and in vivo pharmacology studies.
- Clear chemical identifiers for traceability (CAS, formula, molecular weight).
Medchemexpress LLC GW806742X hydrochloride | 98.3% | 610.01 | 5 MG
GW806742X hydrochloride is an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor. It binds the MLKL pseudokinase domain with a Kd of 9.3 μM and exhibits activity against VEGFR2 with an IC50 of 2 nM. This compound retards MLKL membrane translocation and inhibits necroptosis. This product is for research use only.
- Potent MLKL inhibitor
- Activity against VEGFR2 (IC50=2 nM)
- Retards MLKL membrane translocation
- Inhibits necroptosis